Functional Healing & Energy Restoration

Mucosal Barrier Assessment (Blood Spot Test)

 

The Mucosal Barrier Assessment is a simple blood spot test that evaluates the health and integrity of your gut’s mucosal lining, helping you understand how your digestive system is functioning and how well your body is managing inflammatory and immune responses.

 

This test measures three key markers:

1. Zonulin – A protein that helps regulate intestinal permeability, or “gut barrier” function. Elevated zonulin can indicate a leaky gut, where the intestinal lining becomes more permeable than it should be, allowing toxins or partially digested food particles to enter the bloodstream.

2. Diamine Oxidase (DAO) – An enzyme responsible for breaking down histamine in the digestive tract. Low DAO levels can lead to difficulty processing histamine, which may contribute to digestive discomfort, headaches, or inflammatory responses.

3. Histamine – A chemical involved in immune response, digestion, and inflammation. Elevated histamine levels can indicate histamine intolerance or increased inflammatory activity in the gut.

4. DAO/Histamine Ratio – The relationship between DAO and histamine provides insight into histamine regulation efficiency. An imbalance may suggest poor histamine breakdown, contributing to digestive symptoms, skin reactions, headaches, or general inflammatory stress.

 

Why This Test is Useful

• Detects leaky gut or increased intestinal permeability

• Evaluates your ability to process and regulate histamine

• Identifies imbalances that may contribute to digestive discomfort, inflammation, or immune sensitivity

• Guides targeted nutrition, lifestyle, and supplement strategies to support gut health

 

The Mucosal Barrier Assessment gives you actionable insight into the health of your gut lining and histamine metabolism, allowing for personalized approaches to improve digestion, reduce inflammation, and support overall wellness.

 

Price for test without shipping: $174